产品货号：
Z23516
中文名称：
PJA1抗体
英文名称：
Anti-PJA1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PJA1 Antibody |
| 指标别名 | PJA1,praja ring finger 1,Praja1,RING finger protein 70,RNF70 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | PJA1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | PJA1 antibody was raised against a 19 amino acid peptide near the amino terminus of human PJA1.The immunogen is located within amino acids 50 - 100 of PJA1. |
| 计算分子量 | 71kDa |
| 成分 | PJA1 antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PJA1 antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Ubiquitinization is an important cellular degradation process requiring sequential reactions that are mediated by three enzymes:E1,E2 and E3.PJA1,also known as Praja1 and RING finger protein 70,is a 643 amino acid E2-dependent E3-ubiquitin ligase that is abundantly expressed in the brain (1,2).Through interaction and activation with the E2-ubiquitin ligase UBC4,PJA1 mediates substrate-specific ubiquitination via its RING finger domain and facilitates ubiquitination (3).Overexpression of PJA1 in gastrointestinal cancers suggests that it may be responsible for the degradation of some anti-oncogenic proteins (4,5). |
| Uniprot ID | Q8NG27 |
| 基因名全称 | Praja ring finger 1,E3 ubiquitin protein ligase |
| 蛋白名全称 | Praja ring finger 1,E3 ubiquitin protein ligase |
| 推荐稀释比 | PJA1 antibody can be used for detection of PJA1 by Western blot at 0.25 ～ 0.5μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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